• Skip to main content
  • Skip to secondary menu
  • Skip to primary sidebar
  • Skip to footer

The Optimizing Blog

  • Supplements
  • Nootropics
  • Mushrooms
  • Lifestyle
  • Finance

AstraGin® Gut Health & Absorption Supplement – Review & Guide

Last Updated: August 21, 2021 No Comments – 4 min. read

astragalus flower

AstraGin® is a patented combination of astragalus and ginseng root from NuLiv Science with clinical evidence for boosting nutrient absorption and gut health. Here we’ll examine its properties, research, effects, and applications.

Disclosure:  Some of the links on this page are referral links. At no additional cost to you, if you choose to make a purchase after clicking through those links, I will receive a small commission. This allows me to continue producing high-quality, ad-free content on this site and pays for the occasional cup of coffee. I have first-hand experience with every product or service I recommend, and I recommend them because I genuinely believe they are useful, not because of the commission I get if you decide to purchase through my links. Read more here.

In a hurry? Here are the highlights:

  • AstraGin® is a patented combination of purified, pharmaceutical-grade Panax notoginseng and Astragalus membranaceus from NuLiv Science, Inc.
  • It has clinical evidence for boosting nutrient absorption, immune function, gut health, and protein synthesis.
  • AstraGin® can be especially useful in a pre-workout setting where augmented glucose uptake and protein synthesis would be desirable.

Product Mentions:

– Jacked Factory Build XT Powder
– Jacked Factory Build XT Capsules

Contents

  • What is AstraGin?
  • AstraGin Benefits
  • AstraGin Review
  • AstraGin vs. BioPerine (Piperine)
  • Is AstraGin Safe?
  • AstraGin Supplements
    • Build XT™ Powder
    • Build XT™ Capsules

What is AstraGin?

AstraGin® is a patented combination of purified, pharmaceutical-grade Panax notoginseng and Astragalus membranaceus from NuLiv Science, Inc. that helps optimize gut health and nutrient absorption. AstraGin® has been referred to as a “gut nutraceutical”​1,2​.

astragin logo

AstraGin Benefits

AstraGin® has clinical evidence showing that it may:

  • Increase the absorption of peptides, amino acids, fatty acids, vitamins, and phytonutrients.
  • Rejuvenate ulcerated and damaged intestinal walls and reduce intestinal submucosa inflammation.
  • Support the digestive system by maintaining a healthy microbiota population.
  • Help support stronger immune functions.
  • Increase muscle protein synthesis via enhancing liver ATP production and amino acid uptake.

AstraGin Review

Gut health significantly impacts immunity, sleep, cardiovascular health, cognition, sleep, and more. The integrity of the gut microbiota is important for the correct and optimal absorption of nutrients. Nutritional substances – glucose, amino acids, vitamins, etc. – are absorbed along the entire GI tract. In the cases of glucose and amino acids, special transporters and channels are utilized for absorption. These active transporters are mediated by the enzyme mRNA.

Chang, Huang, Wang, et al demonstrated that AstraGin® seems to significantly enhance glucose uptake via modulation of mRNA expression levels of the Na+/glucose cotransporter 1 (SGLT1) gene​3–5​.

Lee et al noted that, through modulating the mTOR signaling pathway, AstraGin® augments amino acid uptake and subsequent protein synthesis and “can contribute to epithelial barrier repair following intestinal injury, and may offer a therapeutic avenue in treating irritable bowel disease”​6​.

The video below from NuLiv Science summarizes these mechanisms:

Click for Transcript

90% of absorption occurs in the small intestine. Many nutrients we consume such as turmeric or calcium are either marginally or poorly absorbed by the body. AstraGin enhances nutrient uptake by activating certain transporter molecules in your small intestine, allowing more nutrients to cross the intestinal lumen and into the bloodstream for use by our organs, muscles, and more. AstraGin – better health through better absorption

AstraGin® can be useful anytime you want to enhance absorption of other supplements, especially in a pre-workout setting where augmented glucose uptake and protein synthesis would be desirable.

AstraGin vs. BioPerine (Piperine)

AstraGin® seems to have complex mechanisms, the most important of which appears to be the modulation of certain mRNA transporters (SLGT1, GLUT4, CAT1, etc.) to move and improve the absorption of glucose, amino acids, and more​3–5​.

BioPerine® (piperine; black pepper extract), on the other hand, inhibits the drug transporter P-glycoprotein and the drug-metabolizing enzyme CYP3A4, thereby preventing or delaying the breakdown and elimination of compounds taken alongside it. BioPerine® is most commonly seen paired with things like curcumin that have inherently poor bioavailability​7​.

Theoretically, AstraGin® and BioPerine® taken together should be able to enhance absorption more than either by itself.

Is AstraGin Safe?

AstraGin® has GRAS (Generally Regarded As Safe) status from the FDA. This means it is also safe at 100x the recommended dose. Thus, AstraGin® is safe for human consumption at normal dosages.

Talk to your doctor before taking AstraGin® with prescription medication, as it may affect its metabolism.

AstraGin Supplements

AstraGin® has begun to be included in many pre-workout supplements to increase bioavailability and utilization. It should go great with things like creatine monohydrate, PeakO2®, and ElevATP®. Luckily, Build XT™ from Jacked Factory does exactly that. It’s available in powder or capsule form.

Build XT™ Powder

Check Price on Amazon

Build XT™ Capsules

Check Price on Amazon

References

  1. 1.
    NuLiv Science. A full spectrum gut health nutraceutical for absorption, gut lining health, and gut microbiota. NuLiv Science. https://nulivscience.com/ingredients/astragin.
  2. 2.
    NuLiv Science Inc. Method for enhancing nutrient absorption with astragalosides. April 2009. https://patents.google.com/patent/US8197860B2/en.
  3. 3.
    Wang C-W, Huang Y-C, Chan F-N, et al. A gut microbial metabolite of ginsenosides, compound K, induces intestinal glucose absorption and Na+/glucose cotransporter 1 gene expression through activation of cAMP response element binding protein. Mol Nutr Food Res. March 2015:670-684. doi:10.1002/mnfr.201400688
  4. 4.
    Huang Y-C, Lin C-Y, Huang S-F, Lin H-C, Chang W-L, Chang T-C. Effect and Mechanism of Ginsenosides CK and Rg1 on Stimulation of Glucose Uptake in 3T3-L1 Adipocytes. J Agric Food Chem. May 2010:6039-6047. doi:10.1021/jf9034755
  5. 5.
    Chang T-C, Huang S-F, Yang T-C, Chan F-N, Lin H-C, Chang W-L. Effect of Ginsenosides on Glucose Uptake in Human Caco-2 Cells Is Mediated through Altered Na+/Glucose Cotransporter 1 Expression. J Agric Food Chem. March 2007:1993-1998. doi:10.1021/jf062714k
  6. 6.
    Lee S-Y, Tsai W-C, Lin J-C, et al. Astragaloside II promotes intestinal epithelial repair by enhancing L-arginine uptake and activating the mTOR pathway. Sci Rep. September 2017. doi:10.1038/s41598-017-12435-y
  7. 7.
    Shoba G, Joy D, Joseph T, Majeed M, Rajendran R, Srinivas P. Influence of Piperine on the Pharmacokinetics of Curcumin in Animals and Human Volunteers. Planta Med. May 1998:353-356. doi:10.1055/s-2006-957450

Medical Disclaimer:  While I love diving into and extracting useful information from clinical research related to health, fitness, supplements, and more, I am in no way a medical expert. The content on this website is for informational purposes only; it is not professional medical advice, nor is it a substitute for professional medical advice. None of the statements on this website have been evaluated by the FDA. Products mentioned are not intended to diagnose, treat, cure, or prevent any disease. Read my lengthier medical disclaimer here.

Related Posts

  • 8 Important SEO Trends to Watch in 2018 and How to Capitalize on Them
  • 3 Things You Can Do Today to Make Your Magento Website More SEO-Friendly
  • Dynamine™ (Methylliberine) – The Ultimate Guide and Review
  • ElevATP® (Ancient Peat and Apple Extract) – Guide & Review
  • TeaCrine® (Theacrine) – The Ultimate Guide and Review

About John Williamson

Analytical and entrepreneurial-minded data nerd, usability enthusiast, armchair research scientist, health/nutrition/supplement aficionado, and Oxford comma advocate. I lead the Paid Search marketing efforts at Gild Group. I'm not a big fan of social media, but you can find me on LinkedIn and Reddit.

Reader Interactions

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Primary Sidebar

Most Popular

Theobromine – The Ultimate Guide and Review

The 10 Best Nootropics for Studying, Focus, and Memory

How to Repair Dopamine Receptors Naturally – 10 Ways to Upregulate

The 12 Best Nootropics for Motivation – The Ultimate List

Genius Mushrooms Review – Nootropic Mushroom Supplement

The Top 3 Best Mushroom Supplements Blends Reviewed (2022)

Freshcap Thrive 6 Mushroom Extract Powder Review

TeaCrine® (Theacrine) – The Ultimate Guide and Review

PeakO2® Mushroom Supplement – The Ultimate Guide & Review

Dynamine™ (Methylliberine) – The Ultimate Guide and Review

How Rutaecarpine Eliminates Caffeine from the Body to Improve Sleep

freshcap mushrooms

Footer

Amazon Affiliate Disclosure

The Optimizing Blog is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to amazon.com.

  • Facebook
  • Instagram
  • LinkedIn
  • Pinterest
  • RSS
  • Twitter
  • Reddit
  • Supplements
  • Nootropics
  • Mushrooms
  • Lifestyle
  • Finance

Copyright © 2022 TheOptimizingBlog.com


About - Privacy - Terms - Contact

This website uses cookies to improve your experience. We'll assume you're ok with this, but you can opt-out if you wish. Ok, Got ItReject Read More
Privacy & Cookies Policy

Privacy Overview

This website uses cookies to improve your experience while you navigate through the website. Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. We also use third-party cookies that help us analyze and understand how you use this website. These cookies will be stored in your browser only with your consent. You also have the option to opt-out of these cookies. But opting out of some of these cookies may affect your browsing experience.
Necessary
Always Enabled
Necessary cookies are absolutely essential for the website to function properly. This category only includes cookies that ensures basic functionalities and security features of the website. These cookies do not store any personal information.
Non-necessary
Any cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. It is mandatory to procure user consent prior to running these cookies on your website.
SAVE & ACCEPT